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Promethazine hydrochloride tablets, USP are contraindicated in comatose states, and in men and women known being hypersensitive or to obtain had an idiosyncratic reaction to promethazine or to other phenothiazines.

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Excessively high dosages of promethazine hydrochloride have brought about sudden death in pediatric sufferers, Whilst slumber apnea, and sudden infant Demise syndrome (SIDS) have already been claimed in several infants and youthful little ones who ended up getting standard dosages of promethazine hydrochloride or trimeprazine (not commercially available from the US). The connection on the medication and probable mechanism(s) of these kinds of effects have not been elucidated.

Induction of emesis normally really should not be tried, considering that a phenothiazine-induced dystonic response of the head or neck may well lead to aspiration of vomitus through emesis; centrally acting emetics are of very little value from the management of promethazine overdosage. Administration of the saline cathartic could be effective in boosting evacuation of the drug through the GI tract.

Due to elevated possibility of sedative results and confusion (affiliated with promethazine) as well as better frequency of decreased hepatic, renal, and/or cardiac operate and of concomitant sickness and drug therapy in geriatric sufferers, the producers recommend that individuals Within this age group acquire Original dosages click here from the drug during the lower conclude of the same old assortment.

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Retail store get more info at home temperature away from light-weight and dampness. Do not retail outlet in the bathroom. Retain all medicines faraway from youngsters and Animals.

This medication may perhaps interfere with particular lab assessments website (like urine pregnancy tests, skin allergy checks), maybe producing Bogus test final results. Ensure lab staff and all of your Physicians know you utilize this drug.

Geriatric Use Clinical studies of promethazine hydrochloride tablets, USP did not contain adequate numbers of topics aged sixty five and above to determine whether they answer in a different way from younger topics. Other described medical experience hasn't determined variances in responses between the aged and youthful sufferers.

Go to your treatment group for normal checks on the development. Inform your care group if signs or symptoms will not start to get well or if they worsen.

Stimulation could possibly be evident, especially in little ones and geriatric individuals. Convulsions may well rarely take place. A paradoxical-style reaction is described in youngsters obtaining one doses of 75 mg to 125 more info mg orally, characterized by hyperexcitability and nightmares.

When you are prescribed this medication on a regular plan and overlook a dose, get it once you keep in mind. Whether it is close to the time of the next dose, skip the skipped dose. Consider your next dose with the regular time. Usually do not double the dose to catch up.